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成果及论文

1.Hu,L.#,Li,Z.#,Cheng,J.#,Rao,Q.,Gong,W.,Liu,M.,Shi,YG.,Zhu,J.,Wang,P.andXu,Y.*CrystalStructureofTET2-DNAComplex:InsightintoTET-Mediated5mCOxidation,Cell155,1545-1555,2013 2.Fang,R.#,Chen,F.#,Dong,Z.,Hu,D.,Barbera,A.J.,Clark,E.A.,Fang,J.,Yang,Y.,Mei,P.,Rutenberg,M.,Li,Z.,Zhang,Y.,Xu,Y.,Yang,H.,Wang,P.,Simon,M.D.,Zhou,Q.,Li,J.,Marynick,M.P.,Li,X.,Lu,H.,Kaiser,U.B.,Kingston,R.E.,Xu,Y.*,andShi,Y.G.*LSD2/KDM1BanditscofactorNPAC/GLYR1endowastructuralandmolecularmodelforregulationofH3K4demethylation,Molecularcell49,558-570,2013 3.Chen,F.#,Yang,H.#,Dong,Z.#,Fang,J.,Wang,P.,Zhu,T.,Gong,W.,Fang,R.,Shi,Y.G.,Li,Z.*,andXu,Y.*StructuralinsightintosubstraterecognitionbyhistonedemethylaseLSD2/KDM1b,Cellresearch23,306-309,2013 4.Cheng,J.,Yang,Y.,Fang,J.,Xiao,J.,Zhu,T.,Chen,F.,Wang,P.,Li,Z.,Yang,H.,andXu,Y.*StructuralinsightintocoordinatedrecognitionoftrimethylatedhistoneH3lysine9(H3K9me3)bytheplanthomeodomain(PHD)andtandemtudordomain(TTD)ofUHRF1(ubiquitin-like,containingPHDandRINGfingerdomains,1)protein,TheJournalofbiologicalchemistry288,1329-1339,2013 5.Ma,H.#,Chen,H.#,Guo,X.#,Wang,Z.,Sowa,M.E.,Zheng,L.,Hu,S.,Zeng,P.,Guo,R.,Diao,J.,Lan,F.,Harper,J.W.,Shi,Y.G.,Xu,Y.*,andShi,Y.*MphasephosphorylationoftheepigeneticregulatorUHRF1regulatesitsphysicalassociationwiththedeubiquitylaseUSP7andstability,ProceedingsoftheNationalAcademyofSciencesoftheUnitedStatesofAmerica109,4828-4833,2012 6.Yang,Y.#,Hu,L.#,Wang,P.#,Hou,H.,Lin,Y.,Liu,Y.,Li,Z.,Gong,R.,Feng,X.,Zhou,L.,Zhang,W.,Dong,Y.,Yang,H.,Lin,H.,Wang,Y.,Chen,C.D.*,andXu,Y.*Structuralinsightsintoadual-specificityhistonedemethylaseceKDM7AfromCaenorhabditiselegans,Cellresearch20,886-898,2010 7.Hu,L.#,Li,Z.#,Wang,P.,Lin,Y.,andXu,Y.*CrystalstructureofPHDdomainofUHRF1andinsightsintorecognitionofunmodifiedhistoneH3arginineresidue2,Cellresearch.21(9):1374-8,2011 8.Gong,R.#,Li,L.#,Liu,Y.#,Wang,P.,Yang,H.,Wang,L.,Cheng,J.,Guan,K.L.,andXu,Y.*CrystalstructureoftheGtr1p-Gtr2pcomplexrevealsnewinsightsintotheaminoacid-inducedTORC1activation,Genes&development25,1668-1673,2011 9.Li,Z.#,Zhao,B.#,Wang,P.,Chen,F.,Dong,Z.,Yang,H.,Guan,K.L.*,andXu,Y.*StructuralinsightsintotheYAPandTEADcomplex,Genes&development24,235-240,2010